Fas ligand

Fas ligand
Ligand for the Fas antigen which is actually a receptor of the TNF-receptor family.

Dictionary of molecular biology. 2004.

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  • Fas ligand — (FasL) is a type II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. The binding of Fas ligand with its receptor induces apoptosis. Fas ligand receptor interactions play an important role in the regulation of the… …   Wikipedia

  • Fas — (APO 1, CD95) [1] est une protéine transmembranaire appartenant à la famille du récepteur du TNF, pouvant médier la mort par apoptose de cellules transformées mais aussi de lymphocytes T humaines activées. Le signal de mort cellulaire peut être… …   Wikipédia en Français

  • Fas — can mean the following:* Fas receptor, an important cell surface receptor protein of the TNF receptor family known also as CD95, that induces apoptosis on binding Fas ligand. * Fes, Morocco, the third largest city in Morocco, as an alternate… …   Wikipedia

  • Fas-associated phosphatase — is a molecule that inhibits the effect of Fas ligand to make cells initiate apoptosis.ReferencesMolecular cell biology. Lodish, Harvey F. 5. ed. : New York : W. H. Freeman and Co., 2003, 973 s. b ill.ISBN 0 7167 4366 3 …   Wikipedia

  • Fas receptor — The Fas receptor (FasR) is the most intensely studied death receptor. Its aliases include CD95, Apo 1, and tumor necrosis factor receptor superfamily, member 6 (TNFRSf6). The gene is situated on chromosome 10 in humans and 19 in mice.… …   Wikipedia

  • fas gene — The gene that is active in target cells which are susceptible to killing by cells expressing the Fas ligand, a member of the TNF family of cytokines and cell surface molecules …   Dictionary of microbiology

  • Ligand (biochemistry) — Myoglobin (blue) with its ligand heme (orange) bound. Based on PDB 1MBO For other uses of Ligand , see Ligand (disambiguation). In biochemistry and pharmacology, a ligand (from the …   Wikipedia

  • Fas — A receptor present in cells that binds with F. ligand to induce apoptosis. SEE ALSO: F. ligand. * * * Family Attitude Scale; fatty acid synthetase; Federation of American Scientists; fetal akinesia sequence; fetal alcohol syndrome * * * FAS abbr… …   Medical dictionary

  • ligand — 1. Any individual atom, group, or molecule attached to a central metal ion by multiple coordinate bonds; e.g., the porphyrin portion of heme, the corrin nucleus of the B12 vitamins. 2. An …   Medical dictionary

  • APO-1 — Fas Fas (APO 1, CD95) [1] est une protéine transmembranaire appartenant à la famille du récepteur du TNF, pouvant médier la mort par apoptose de cellules transformées mais aussi de lymphocytes T humaines activées. Le signal de mort cellulaire… …   Wikipédia en Français

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